Lipid rafts - The plasma membrane is composed of a lipid bilayer inserted various proteins(transmembrane ion-channel and transporter proteins). Many of these proteins are found associated with surface of the membrane which are rich in free cholesterol and sphingolipids (lipids containing the amino acid sphingosine ).
Lipid rafts are more ordered and tightly packed than the surrounding bilayer, but float freely in the membrane bilayer.
Lipid rafts generally contain 3 to 5-fold the amount of cholesterol found in the surrounding bilayer. Also, lipid rafts are enriched in sphingolipids such as sphingomyelin and play important roles in signal transduction .
https://www.researchgate.net/figure/230685775_fig6_Fig-12-Structure-and-formation-of-lipid-rafts-based-on-a-lipid-ordering-disordering
Types of lipid rafts-
1.Caveolae type- Flask shaped invaginations in plasma membrance which is riched in caveolin.
2.Planar lipid rafts- Found in neurons and enriched in flotilin.
3.Glycospingolipid enriched membranes (GEM)
4.Polyphosphoinositol rafts
http://www.getmededu.com/plasma-or-cell-membrane.html
FUNCTIONS -
1.Provide stability or rigidity .
2.Helps in signal transduction.
3.In endocytosis it helps.
4.Cholesterol transport .
Lipid rafts are more ordered and tightly packed than the surrounding bilayer, but float freely in the membrane bilayer.
Lipid rafts generally contain 3 to 5-fold the amount of cholesterol found in the surrounding bilayer. Also, lipid rafts are enriched in sphingolipids such as sphingomyelin and play important roles in signal transduction .
Types of lipid rafts-
1.Caveolae type- Flask shaped invaginations in plasma membrance which is riched in caveolin.
2.Planar lipid rafts- Found in neurons and enriched in flotilin.
3.Glycospingolipid enriched membranes (GEM)
4.Polyphosphoinositol rafts
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| Types of lipid rafts |
FUNCTIONS -
1.Provide stability or rigidity .
2.Helps in signal transduction.
3.In endocytosis it helps.
4.Cholesterol transport .
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