Friday, 20 May 2016

D- loop replication

D- loop replication-

The mitochondrial Dna  undergoes a process of replication called D- loop replication. It is found in circular Dna. Mitochondrial Dna is circular like plasmid. It is made up of 2 strands-

1.L-strand(light strand)
2.H-strand(heavy strand)

There are 2 different origin of replications ,one for light strand and one for heavy strand. The process of replication starts from origin of heavy strand. Replication in case of mitochondia is semiconservative . Heavy strand act as a leading strand and form displacememt loops .The loop expands as the process elongate. As a result of this a new light strand form by displacing the parental strand, whose replication structure is resembles to the letter D . When displaced strand passes the origin of replication of L-strand a new H -strand  synthesis starts. Because of replication structure D this mode of replication is called as D-loop replication of mitochondrial Dna.


Image source -http://slideplayer.com/slide/2758294/


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