Frame shift mutation -
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Image source-http://www.slideshare.net/rajdangol303/mutation-35776184
- Mutation is a sudden change in nucleotide sequence.
- It is the addition or deletion of base pair that occurs within the protein coding portion of a gene which have the effect of shifting the translational reading frame.
- In frame shift mutation each codon acts as an open reading frame.
- It disrupts the translation changing the reading frame due to addition or deletion and Proteins are built incorrectly.
Image source -http://www.slideshare.net/openmichigan/081308d-ginsburgdnaseq-variation
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