Tuesday 17 May 2016

Pedigree analysis-autosomal dominant example



Image source https://en.wikipedia.org/wiki/Cancer_syndrome#/media/File:Autosomal_dominant.png

Autosomal dominant example-
  • The disease occur with 3 consecutive generations (Aa), this never happens with recessive traits.
  • Males and females are affected equally but with exception in some case.
  • Affected children (aa)will usually have an affected parents(Aa).
  • Two affected parents (Aa)can have uninfected child(aa).
  • Two unaffected parents(aa) will not have affected children(aa).
  •  Examples of autosomal dominant diseases include Huntington disease, neurofibromatosis and polycystic kidney disease.
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