Monday 30 May 2016

Pleiotrophy

Pleiotrophy - One gene have the ability to produce two or more unrelated phenotypic traits. 
An example is phenylketonuria.
The disease causes mental retardation, reduded hair and pigmentation.
Due to mutation in a single gene phenylalanine to tyrosine.




                            Image source-http://mumtazticloft.com/PigeonGenetics1.asp

Other examples are-
1.Sickle cell anemia -enlarged spleen,muscle pain,low RBC count
2.AlbinismAlbinism is also a pleiotropic trait affecting eyesight as well as resulting in a lack of pigmentation in skin, hair, and eyes.
3.Cytokines that have different biological functions.



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