RNA FLASH CARD

1.MYC -----------------------------------------------------------Transcription factor helps in activation(CSIR)
2,Retinoids upregulate trascription----------------------------1 and 7 collagens
3.Heavy methylated Dna----------------------------------------Low transcription

4.Types        (CSIR QUESTIONS )  DNA   OF BIOSCIENCE 
a.Heterohenous nuclear Rna ---------------------------------precursor of other RNAs
b.Sc RNA -------------------------------------------------------selection of protein for export
c.Sno-RNA------------------------------------------------------r-RNA processing
d.Sn-RNA -------------------------------------------------------m-RNA processing

5.TRANSCRIPTION FACTORS-
a.TF II A-------------------------------------------------------promoter recognition,nuclear origin,RNApol II                                                                                                forming pre-                                                                                                                                                             inititaion complex
b.TF II B-------------------------------------------------------                   do ------
c.TF II D-------------------------------------------------------TBP (Tata binding protein) is the subunit .TATA                                                                                        Ssequence is recognized by TFII D.
d,TF II E------------------------------------------------------Melting of DNA,  consist of zinc finger motif
e.TF II F-----------------------------------------------------Stabilize the Rna pol II
f.TH II H ---------------------------------------------------nucleotide excision repair,xeroderma                                                                                                                  pigmentosum  (CSIR QUESTION)

DNA   OF BIOSCIENCE 

6.Retroviral genome(contains 3 proteins)(CSIR QUESTION)
a.Gag --------------------------------------------------------It produce capsid proteins(p24 and p17)
b.Pol----------------------------------------------------------Reverse transcriptase,RNase H ,integrase                                                                                                       function & code for proteases.
c.env---------------------------------------------------------Resides in lipd layer, proteins of viral envelope                                                                                             also called transmembrane proteins(gp 41,gp 120)
DNA   OF BIOSCIENCE 
7.Inhibitors-
a.Alpha amanitin---------------------------------------------eukaryotic RNA pol II (CSIR QUESTION)
b.Actinomycin D------------------------------------------Blocks elongation of bacterial RNA pol.
c.Rifampicin----------------------------------------------bind to beta subunit of RNA pol .
d.Azidothymidine(AZT)-------------------------------Reverse transcriptase inhibition


8. Leucine zipper ------------------------------------Transcription factor

9.2'OH group in RNA ---------------------------------Transesterification

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